Ivacaftor (trade name Kalydeco, developed as VX-770) is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR.
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2.Consistent quality
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Product name Ivacaftor
CAS NO. 873054-44-5
Synonyms Ivacaftor
Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity 99% Ivacaftor
Appearance Ivacaftor powder
Shelf life 2 years for Ivacaftor
Usage Ivacaftor(VX-770) is a drug approved for patients with a certain mutation of cystic fibrosis.
Storage Ivacaftor should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Note: Ivacaftor for R&D use only.
CAS NO. 873054-44-5
Synonyms Ivacaftor
Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity 99% Ivacaftor
Appearance Ivacaftor powder
Shelf life 2 years for Ivacaftor
Usage Ivacaftor(VX-770) is a drug approved for patients with a certain mutation of cystic fibrosis.
Storage Ivacaftor should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Note: Ivacaftor for R&D use only.
Specifications:
Item Specification
Specific rotation +39.5 to +41.5°
State of solution(transmittance) Clear 98.0% min.
Chloride[cl] 0.020% max.
Ammonium [NH4] 0.02% max.
Sulfate[SO4] 0.020% max
Iron[Fe] 10ppm max.
Heavy metals [Pb] 10ppm max
Arsenic[As2O3] 1ppm max
Other amino acids Chromatographically not detectable
Loss on drying 0.20% max.
Residue on ignition[sulfated] 0.10% max.
Assay 99.0% min
Packaging & Shipping:
Specific rotation +39.5 to +41.5°
State of solution(transmittance) Clear 98.0% min.
Chloride[cl] 0.020% max.
Ammonium [NH4] 0.02% max.
Sulfate[SO4] 0.020% max
Iron[Fe] 10ppm max.
Heavy metals [Pb] 10ppm max
Arsenic[As2O3] 1ppm max
Other amino acids Chromatographically not detectable
Loss on drying 0.20% max.
Residue on ignition[sulfated] 0.10% max.
Assay 99.0% min
Packaging & Shipping:
Ivacaftor Packaging:
1g,5g,10g,50g,100g/bottle.
1kg/tin for trial order.
25kg/drum for commercial quantity.
Specific packing required by customer.
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